Richard K. Plemper: search on Z-Library

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1

Identification and Characterization of Influenza Virus Entry Inhibitors Through Dual-Myxovirus High-Throughput Screening

Weisshaar, Marco, Cox, Robert, Morehouse, Zachary, Kyasa, ShivaKumar, Yan, Dan, Oberacker, Phil, Mao, Shuli, Golden, Jennifer E, Lowen, Anice C, Natchus, Michael G, Plemper, Richard K

Journal:

Journal of Virology

Year:

2016

File:

PDF, 5.04 MB

2016

2

Non-nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase: Synthesis, Structure–Activity Relationships, and Pharmacokinetics

Ndungu, J. Maina, Krumm, Stefanie A., Yan, Dan, Arrendale, Richard F., Reddy, G. Prabhakar, Evers, Taylor, Howard, Randy, Natchus, Michael G., Saindane, Manohar T., Liotta, Dennis C., Plemper, Richard

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

3

Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Prussia, Andrew, Thepchatri, Pahk, Snyder, James P., Plemper, Richard

Journal:

International Journal of Molecular Sciences

Year:

2011

Language:

english

File:

PDF, 729 KB

english, 2011

4

Sequential Conformational Changes in the Morbillivirus Attachment Protein Initiate the Membrane Fusion Process

Ader-Ebert, Nadine, Khosravi, Mojtaba, Herren, Michael, Avila, Mislay, Alves, Lisa, Bringolf, Fanny, Örvell, Claes, Langedijk, Johannes P., Zurbriggen, Andreas, Plemper, Richard K., Plattet, Philippe,

Journal:

Year:

2015

Language:

english

File:

PDF, 12.19 MB

english, 2015

5

Organization, Function, and Therapeutic Targeting of the Morbillivirus RNA-Dependent RNA Polymerase Complex

Sourimant, Julien, Plemper, Richard

Journal:

Year:

2016

Language:

english

File:

PDF, 4.27 MB

english, 2016

6

Biology must develop herd immunity against bad-actor molecules

Plemper, Richard K., Cox, Robert M., Spindler, Katherine R.

Journal:

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

7

Measles Resurgence and Drug Development

Plemper, Richard K

Journal:

Current Opinion in Virology

Year:

2020

File:

PDF, 1.21 MB

2020

8

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation

Aiming Sun, Nizal Chandrakumar, Jeong-Joong Yoon, Richard K. Plemper, James P. Snyder

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

9

10.1038/42276

Plemper, Richard K., Böhmler, Sigrun, Bordallo, Javier, Sommer, Thomas, Wolf, Dieter H.

Journal:

Year:

1997

Language:

english

File:

PDF, 331 KB

english, 1997

10

Endoplasmic reticulum degradation. Reverse protein transport and its end in the proteasome

Richard K. Plemper, Dieter H. Wolf

Journal:

Molecular Biology Reports

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

11

Retrograde protein translocation: ERADication of secretory proteins in health and disease

Richard K Plemper, Dieter H Wolf

Journal:

Trends in Biochemical Sciences

Year:

1999

Language:

english

File:

PDF, 637 KB

english, 1999

12

Re-entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species

Richard K. Plemper, Peter M. Deak, Ralf T. Otto, Dieter H. Wolf

Journal:

Year:

1999

Language:

english

File:

PDF, 462 KB

english, 1999

13

Host-Directed Inhibitors of Myxoviruses: Synthesis and in Vitro Biochemical Evaluation

Sun, Aiming, Ndungu, J. Maina, Krumm, Stefanie A., Yoon, Jeong-Joong, Thepchatri, Pahk, Natchus, Michael, Plemper, Richard K., Snyder, James P.

Journal:

ACS Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

14

A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesis

Hotard, Anne L., Shaikh, Fyza Y., Lee, Sujin, Yan, Dan, Teng, Michael N., Plemper, Richard K., Crowe, James E., Moore, Martin L.

Journal:

Year:

2012

Language:

english

File:

PDF, 653 KB

english, 2012

15

Cell entry of enveloped viruses

Richard K Plemper

Journal:

Current Opinion in Virology

Year:

2011

Language:

english

File:

PDF, 527 KB

english, 2011

16

Potent Non-Nucleoside Inhibitors of the Measles Virus RNA-Dependent RNA Polymerase Complex

Sun, Aiming, Yoon, Jeong-Joong, Yin, Yan, Prussia, Andrew, Yang, Yutao, Min, Jaeki, Plemper, Richard K., Snyder, James P.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 322 KB

english, 2008

17

Structural Features of Paramyxovirus F Protein Required for Fusion Initiation †

Plemper, Richard K., Lakdawala, Ami S., Gernert, Kim M., Snyder, James P., Compans, Richard W.

Journal:

Year:

2003

Language:

english

File:

PDF, 1.17 MB

english, 2003

18

Measles Virus Entry Inhibitors: A Structural Proposal for Mechanism of Action and the Development of Resistance †

Prussia, Andrew J., Plemper, Richard K., Snyder, James P.

Journal:

Year:

2008

Language:

english

File:

PDF, 14.11 MB

english, 2008

19

Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein That Modulate Fusion Activity and Pathogenesis

Hotard, Anne L., Lee, Sujin, Currier, Michael G., Crowe, James E., Sakamoto, Kaori, Newcomb, Dawn C., Peebles, R. Stokes, Plemper, Richard K., Moore, Martin L., Lyles, D. S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 4.20 MB

english, 2015

20

Canine Distemper Virus Envelope Protein Interactions Modulated by Hydrophobic Residues in the Fusion Protein Globular Head

Avila, Mislay, Khosravi, Mojtaba, Alves, Lisa, Ader-Ebert, Nadine, Bringolf, Fanny, Zurbriggen, Andreas, Plemper, Richard K., Plattet, Philippe, García-Sastre, A.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 5.74 MB

english, 2015

21

Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity

Matharu, Daljit S., Flaherty, Daniel P., Simpson, Denise S., Schroeder, Chad E., Chung, Donghoon, Yan, Dan, Noah, James W., Jonsson, Colleen B., White, E. Lucile, Aubé, Jeffrey, Plemper, Richard K., S

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 942 KB

english, 2014

22

Synergizing vaccinations with therapeutics for measles eradication

Plemper, Richard K, Hammond, Anthea L

Journal:

Expert Opinion on Drug Discovery

Year:

2014

Language:

english

File:

PDF, 481 KB

english, 2014

23

Recombinant influenza virus carrying the conserved domain of respiratory syncytial virus (RSV) G protein confers protection against RSV without inflammatory disease

Lee, Yu-Na, Suk Hwang, Hye, Kim, Min-Chul, Lee, Young-Tae, Cho, Min-Kyoung, Kwon, Young-Man, Seok Lee, Jong, Plemper, Richard K., Kang, Sang-Moo

Journal:

Year:

2015

Language:

english

File:

PDF, 5.81 MB

english, 2015

24

Measles Virus Glycoprotein Complexes Preassemble Intracellularly and Relax during Transport to the Cell Surface in Preparation for Fusion

Brindley, Melinda A., Chaudhury, Sukanya, Plemper, Richard K., Lyles, D. S.

Journal:

Journal of Virology

Year:

2015

Language:

english

File:

PDF, 1.91 MB

english, 2015

25

Blocking Respiratory Syncytial Virus Entry: A Story with Twists

Weisshaar, Marco, Cox, Robert, Plemper, Richard K.

Journal:

DNA and Cell Biology

Year:

2015

Language:

english

File:

PDF, 502 KB

english, 2015

26

Structural and Mechanistic Studies of Measles Virus Illuminate Paramyxovirus Entry

Plemper, Richard K., Brindley, Melinda A., Iorio, Ronald M., Manchester, Marianne

Journal:

Year:

2011

Language:

english

File:

PDF, 497 KB

english, 2011

27

A Compact, Multifunctional Fusion Module Directs Cholesterol-Dependent Homomultimerization and Syncytiogenic Efficiency of Reovirus p10 FAST Proteins

Key, Tim, Duncan, Roy, Plemper, Richard K.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.38 MB

english, 2014

28

Tunable and reversible drug control of protein production via a self-excising degron

Chung, Hokyung K, Jacobs, Conor L, Huo, Yunwen, Yang, Jin, Krumm, Stefanie A, Plemper, Richard K, Tsien, Roger Y, Lin, Michael Z

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.88 MB

english, 2015

29

Inhibition of Membrane Fusion as a Target for Antiviral Therapy

Plemper, Richard, Hammond, Anthea

Journal:

Anti-Infective Agents in Medicinal Chemistry (Formerly ‘Current Medicinal Chemistry - Anti-Infective Agents)

Year:

2007

Language:

english

File:

PDF, 306 KB

english, 2007

30

Cancer and Virus Leads by HTS, Chemical Design and SEA Data Mining

Thepchatri, Pahk, Min, Jaeki, Ganesh, Thota, Du, Yuhong, Lewis, Iestyn, Kurtkaya, Serdar, Prussia, Andrew, Li, Lian, Sneed, Blossom, Plemper, Richard, Fu, Haian, Liotta, Dennis, Snyder, James, Dingled

Journal:

Current Topics in Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 783 KB

english, 2009

31

Structure-Guided Design of Small-Molecule Therapeutics against RSV Disease

Cox, Robert, Plemper, Richard K

Journal:

Expert Opinion on Drug Discovery

Year:

2016

Language:

english

File:

PDF, 994 KB

english, 2016

32

Releasing the genomic RNA sequestered in the mumps virus nucleocapsid

Severin, Chelsea, Terrell, James R., Zengel, James R., Cox, Robert, Plemper, Richard K., He, Biao, Luo, Ming

Journal:

Journal of Virology

Year:

2016

Language:

english

File:

PDF, 6.47 MB

english, 2016

33

Polymerases of paramyxoviruses and pneumoviruses

Fearns, Rachel, Plemper, Richard K.

Journal:

Year:

2017

Language:

english

File:

PDF, 619 KB

english, 2017

34

The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient

Cox, Robert M., Krumm, Stefanie A., Thakkar, Vidhi D., Sohn, Maximilian, Plemper, Richard K.

Journal:

Science Advances

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

35

Structure and organization of paramyxovirus particles

Cox, Robert M, Plemper, Richard K

Journal:

Current Opinion in Virology

Year:

2017

Language:

english

File:

PDF, 2.63 MB

english, 2017

36

Mutations in the fusion protein of measles virus that confer resistance to the membrane fusion inhibitors carbobenzoxy-d-Phe-l-Phe-Gly and AS-48

Ha, Michael N., Delpeut, Sébastien, Noyce, Ryan S., Sisson, Gary, Black, Karen M., Lin, Liang-Tzung, Bilimoria, Darius, Plemper, Richard K., Privé, Gilbert G., Richardson, Christopher D.

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

37

Cryo-Electron Tomography Provides Insight into the Native Architecture of the Measles Virus Assembly Site

Strauss, Joshua D., Zunlong, Ke, Plemper, Richard K., Wright, Elizabeth R.

Journal:

Microscopy and Microanalysis

Year:

2016

Language:

english

File:

PDF, 17.66 MB

english, 2016

38

The Near-to-Native-State Architecture of Measles Virus Assembly Sites and Isolated Measles Virus Particles

Wright, Elizabeth R., Strauss, Joshua D., Zunlong, Ke, Hampton, Cheri M., Leon, Fredrick, Brindley, Melinda, Plemper, Richard K.

Journal:

Microscopy and Microanalysis

Year:

2017

Language:

english

File:

PDF, 160 KB

english, 2017

39

The Unstructured Paramyxovirus Nucleocapsid Protein Tail Domain Modulates Viral Pathogenesis through Regulation of Transcriptase Activity

Thakkar, Vidhi D, Cox, Robert M, Sawatsky, Bevan, da Fontoura Budaszewski, Renata, Sourimant, Julien, Wabbel, Katrin, Makhsous, Negar, Greninger, Alexander L, von Messling, Veronika, Plemper, Richard

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 4.97 MB

english, 2018

40

Structures of the prefusion form of measles virus fusion protein in complex with inhibitors

Hashiguchi, Takao, Fukuda, Yoshinari, Matsuoka, Rei, Kuroda, Daisuke, Kubota, Marie, Shirogane, Yuta, Watanabe, Shumpei, Tsumoto, Kouhei, Kohda, Daisuke, Plemper, Richard Karl, Yanagi, Yusuke

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.74 MB

english, 2018

41

Promotion of virus assembly and organization by the measles virus matrix protein

Ke, Zunlong, Strauss, Joshua D., Hampton, Cheri M., Brindley, Melinda A., Dillard, Rebecca S., Leon, Fredrick, Lamb, Kristen M., Plemper, Richard K., Wright, Elizabeth R.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 4.42 MB

english, 2018

42

Receptor-Targeted Nipah Virus Glycoproteins Improve Cell-Type Selective Gene Delivery and Reveal a Preference for Membrane-Proximal Cell Attachment

Bender, Ruben R., Muth, Anke, Schneider, Irene C., Friedel, Thorsten, Hartmann, Jessica, Plückthun, Andreas, Maisner, Andrea, Buchholz, Christian J., Plemper, Richard K

Journal:

Year:

2016

Language:

english

File:

PDF, 6.73 MB

english, 2016

43

The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics

Cox, Robert, Plemper, Richard K.

Journal:

Frontiers in Microbiology

Year:

2015

Language:

english

File:

PDF, 2.61 MB

english, 2015

44

Development of an allosteric inhibitor class blocking RNA elongation by the respiratory syncytial virus polymerase complex

Cox, Robert M, Toots, Mart, Yoon, Jeong-Joong, Sourimant, Julien, Ludeke, Barbara, Fearns, Rachel, Bourque, Elyse, Patti, Joseph, Lee, Edward, Vernachio, John, Plemper, Richard K

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 7.32 MB

english, 2018

45

Asymmetric synthesis of host-directed inhibitors of myxoviruses

Moore, Terry W, Sana, Kasinath, Yan, Dan, Thepchatri, Pahk, Ndungu, John M, Saindane, Manohar T, Lockwood, Mark A, Natchus, Michael G, Liotta, Dennis C, Plemper, Richard K, Snyder, James P, Sun, Aimin

Journal:

Beilstein Journal of Organic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.02 MB

english, 2013

46

Engineered small molecule control of influenza A virus replication

Fay, Elizabeth J., Aron, Stephanie L., Stone, Ian A., Waring, Barbara M., Plemper, Richard K., Langlois, Ryan A.

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

47

Primary Resistance Mechanism of the Canine Distemper Virus Fusion Protein against a Small-Molecule Membrane Fusion Inhibitor

Kalbermatter, David, Shrestha, Neeta, Ader-Ebert, Nadine, Herren, Michael, Moll, Pascal, Plemper, Richard K., Altmann, Karl-Heinz, Langedijk, Johannes P., Gall, Flavio, Lindenmann, Urs, Riedl, Rainer,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.99 MB

english, 2018

48

Editorial overview: Antiviral strategies: Antiviral drug development for single-stranded RNA viruses

Brinton, Margo A, Plemper, Richard K

Journal:

Current Opinion in Virology

Year:

2019

Language:

english

File:

PDF, 177 KB

english, 2019

49

Bipartite interface of the measles virus phosphoprotein X domain with the large polymerase protein regulates viral polymerase dynamics

Du Pont, Venice, Jiang, Yi, Plemper, Richard K., Whelan, Sean P.J.

Journal:

Year:

2019

Language:

english

File:

PDF, 11.62 MB

english, 2019

50

Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection

Shi, Zhenda, Zou, Jun, Zhang, Zhan, Zhao, Xu, Noriega, Juan, Zhang, Benyue, Zhao, Chunyu, Ingle, Harshad, Bittinger, Kyle, Mattei, Lisa M., Pruijssers, Andrea J., Plemper, Richard K., Nice, Timothy J.

Journal:

Year:

2019

File:

PDF, 6.53 MB

2019

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